PROCESSES FOR PREPARING OPTICALLY ACTIVE DIAMINE DERIVATIVES

摘要

The present invention addresses the problem of providing an efficient process for preparing important intermediate compounds (1) and (1a) for the production of FXa inhibitors (X) and (X-a). The present invention pertains to: a process which is useful for preparing a compound represented by formula (8d) and which includes stereoselective intramolecular cyclization; and a process which is useful for preparing a compound (1f), a salt thereof or a hydrate of either and which is characterized by including the desulfonylation of a compound (8d). In each formula, R4a is C1-6 alkyl, benzyl or the like.