发明名称 LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING THE SAME USING DISPLACEMENT CHROMATOGRAPHY
摘要 The present invention relates to low acidic species (AR) compositions comprising a protein, e.g., an antibody, or antigen-binding portion thereof, and methods for producing such low AR compositions using displacement chromatography. Methods for using such compositions to treat a disorder, e.g., a disorder in which TNa is detrimental, are also provided.
申请公布号 CA2899449(A1) 申请公布日期 2014.10.02
申请号 CA20142899449 申请日期 2014.03.12
申请人 ABBVIE INC. 发明人 WANG, CHEN;COPPOLA, GERMANO;CHUMSAE, CHRISTOPHER
分类号 C07K1/16;C07K1/20;C07K16/06;C07K16/28 主分类号 C07K1/16
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