发明名称 |
TRICYCLO-PHOSPHOROTHIOATE DNA |
摘要 |
The present invention relates to a nucleic acid molecule containing a sequence of tricyclo nucleosides joined by internucleoside phosphorothioate linkage. The invention also relates to synthetic antisense oligonucleotides and to methods employing the same. |
申请公布号 |
US2014296323(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
US201214351733 |
申请日期 |
2012.10.12 |
申请人 |
ASSOCIATION INSTITUT DE MYOLOGIE ;UNIVERSITAT BERN ;UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) ;INSTITUT NATIONAL DE LA SNATE ET DE LA RECHERCHE MEDICALE ;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
Leumann Christian;Garcia Luis;Voit Thomas |
分类号 |
C12N15/113 |
主分类号 |
C12N15/113 |
代理机构 |
|
代理人 |
|
主权项 |
1. A nucleic acid molecule comprising tricyclo-nucleosides joined by internucleoside phosphorothioate linkages (3′-OPS-O-5′ linkages). |
地址 |
Paris FR |