Methods for identifying subjects having bone loss by detecting bone microparticles in a sample of their bodily fluid are disclosed. Methods for monitoring bone loss and assessing efficacy of bone loss therapies by detecting bone microparticles in bodily fluid samples are also disclosed. Compounds for use as a negative control in the disclosed methods are provided as well as kits comprising such compounds.
申请公布号
WO2014153661(A1)
申请公布日期
2014.10.02
申请号
WO2014CA50312
申请日期
2014.03.26
申请人
LONDON HEALTH SCIENCES CENTRE RESEARCH INC.
发明人
LEONG, HON SING;LUYT, LEONARD;BIGGS, COLLEEN NICOLE;ST. AMANT, ANDRE;LEWIS, JOHN D.;MINUK, LEONARD