发明名称 |
Composition For Promoting Apoptosis Or Inhibiting Cell Growth, Comprising Epstein-Barr Virus Microrna |
摘要 |
Provided is a use of an miRNA of an Epstein-Barr virus (EBV), more specifically, EBV miR-BART4-5p, miR-BART4-3p, miR-BART1-5p, miR-BART15-3p, miR-BART5-5p, miR-BART5-3p, miR-BART16-5p, miR-BART16-3p, miR-BART17-3p, miR-BART21-3p, miR-BART18-5p, miR-BART7-5p, miR-BART9-5p, miR-BART22-5p, miR-BART20-3p, miR-BART13-5p, miR-BART13-3p, miR-BART2-3p, and mimics thereof for promoting apoptosis or inhibiting cell growth. |
申请公布号 |
US2014296319(A1) |
申请公布日期 |
2014.10.02 |
申请号 |
US201214122236 |
申请日期 |
2012.05.24 |
申请人 |
Catholic University Industry Academic Cooperation Foundation |
发明人 |
Lee Suk Kyeong;Choi Hoyun |
分类号 |
C12N15/113;A61K31/713 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
1. A method for preventing or treating a disease selected from the group consisting of a tumor; an autoimmune disease; a lymphoproliferative disease; an inflammatory disease; a viral infection; a restenosis of blood vessels by angioplasty; and a fibrosis by overgrowth of fibroblasts, the method comprising administering to a subject in need thereof an effective amount of a pharmaceutical composition comprising at least one selected from the group consisting of Epstein-Barr virus (EBV) miR-BART4-5p, miR-BART4-3p, miR-BART1-5p, miR-BART15-3p, miR-BART5-5p, miR-BART5-3p, miR-BART16-5p, miR-BART16-3p, miR-BART17-3p, miR-BART21-3p, miR-BART18-5p, miR-BART7-5p, miR-BART9-5p, miR-BART22-5p, miR-BART20-3p, miR-BART13-5p, miR-BART13-3p, miR-BART2-3p and mimics thereof, and a pharmaceutically allowable matrix. |
地址 |
Seoul KR |