发明名称 METHOD FOR ANALYZING BIOMOLECULES AND BIOMOLECULE ANALYZER
摘要 The method for analyzing biomolecules, includes the steps of: immobilizing biomolecules to be analyzed on surfaces of magnetic microparticles; reacting labeled probe molecules with the biomolecules to be analyzed; collecting and immobilizing the microparticles on a support substrate; and measuring a label on the support substrate. Since single-molecule immobilized magnetic microparticles are used in the present invention, the number of biomolecules can be counted, and since hybridization and an antigen-antibody reaction are performed with the microparticles having biomolecules immobilized thereon dispersed, the reaction can be rapidly performed. Further, the type and the abundance of biomolecules of interest can be determined at a single molecular level, so as to evaluate, in particular, the absolute concentration of biomolecules.
申请公布号 US2014295430(A1) 申请公布日期 2014.10.02
申请号 US201214349520 申请日期 2012.10.04
申请人 HITACHI HIGH-TECHNOLOGIES CORPORATION 发明人 Saito Toshiro;Hamasaki Koshin;Takahashi Satoshi;Maeshima Muneo;Imai Kyoko;Imai Kazumichi;Tao Ryuji
分类号 C12Q1/68;G01N33/543 主分类号 C12Q1/68
代理机构 代理人
主权项 1. A method for analyzing biomolecules, comprising the steps of: immobilizing biomolecules to be analyzed on surfaces of magnetic microparticles; reacting labeled probe molecules with the biomolecules to be analyzed; collecting and immobilizing the microparticles on a support substrate; and measuring the labels on the support substrate.
地址 Tokyo JP