发明名称 |
PORCINE KNOB XENOTYPE CHIMERIC ADENOVIRAL VECTOR FOR DENDRITIC CELL INFECTION |
摘要 |
Disclosed are methods of transforming dendritic cells with a chimeric adenovirus-5 (Ad5). A chimeric adenovirus includes a fiber comprising a tail, a shaft and a knob, wherein the knob is a porcine knob, and a nucleic acid comprising a promoter operably linked to a heterologous sequence encoding an antigen peptide. |
申请公布号 |
WO2013090806(A3) |
申请公布日期 |
2014.10.02 |
申请号 |
WO2012US69884 |
申请日期 |
2012.12.14 |
申请人 |
WASHINGTON UNIVERSITY;CURIEL, DAVID |
发明人 |
CURIEL, DAVID |
分类号 |
C12N15/861;A61K39/00;C12N5/0784;C12N15/63 |
主分类号 |
C12N15/861 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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