THERAPEUTIC AGENT FOR PULMONARY HYPERTENSION, WHICH CONTAINS BENZOPHENONE DERIVATIVE OR SALT THEREOF

摘要

A method using a benzophenone derivative represented by general formula (AA) or a salt thereof and a pharmaceutical composition containing the benzophenone derivative or a salt thereof are useful for the treatment or prophylaxis of pulmonary hypertension or heart failure. (In the formula, R1 represents an optionally substituted heterocyclic group, a substituted phenyl group or the like; Z represents an alkylene group or the like; R2 represents a carboxyl group which may be protected by an alkyl group, or the like; R3 represents an optionally protected hydroxyl group or the like; R4 represents an optionally substituted cycloalkyloxy group or the like; and R5 represents a hydrogen atom or the like.)