摘要 |
In certain embodiments, a nano-sized vehicle (e.g., a nanogel comprising nanoparticles) is provided herein for drug delivery with tunable biodistribution, low toxicity, and degradability, and with demonstrated targeting to bone. The composition is useful, for example, in the treatment of bone disease, particularly bone metastases from cancers such as breast, prostate, or lung cancer. |
申请人 |
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
HELLER, DANIEL A.;WALLAS, JASMINE;LEVI, YAIR;PRATT, GEORGE W.;ANDERSON, DANIEL G.;LANGER, ROBERT |