发明名称 |
Disease site-delivering pharmaceutical compositions comprising paclitaxel. |
摘要 |
The invention provides a method for determining the response of a mammalian tumor to a chemotherapeutic agent comprising detecting and quantifying the SPARC protein in a sample isolated from the human. The invention also provides a method for delivering a chemotherapeutic agent to a tumor in a human that expresses SPARC comprising administering a pharmaceutical composition comprising the chemotherapeutic agent coupled to a compound that binds SPARC protein. The invention further provides a composition comprising a chemotherapeutic agent coupled to a compound capable of binding SPARC protein and a pharmaceutically acceptable carrier. |
申请公布号 |
EP2784082(A1) |
申请公布日期 |
2014.10.01 |
申请号 |
EP20140163409 |
申请日期 |
2005.05.16 |
申请人 |
ABRAXIS BIOSCIENCE, LLC |
发明人 |
TRIEU, VUONG;DESAI, NEIL P.;SOON-SHIONG, PATRICK |
分类号 |
C07K14/47;A61K38/39;A61K38/40;A61K39/395;A61K47/48;G01N33/574 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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