发明名称 1-SUBSTITUTED-3- BETA-D-GLYCOPYRANOSYLATED NITROGENOUS HETERO- CYCLIC COMPOUNDS AND MEDICINES CONTAINING THE SAME
摘要 <p>A compound having an SGLT1 and/or SGLT2 inhibitory activity which is usable as an agent for the prevention or treatment of diabetes, postprandial hyperglycemia, impaired glucose tolerance, diabetic complications, obesity, etc. It is a 1-substituted-3-(²-D-glycopyranosyl) nitrogen-containing heterocyclic compound represented by the general formula (I), a prodrug thereof, or a pharmaceutically acceptable salt thereof, or a hydrate or a solvate thereof; an SGLT inhibitor containing the same; a pharmaceutical composition containing the same and a combination pharmacy of them. In the formula, A represents an alkylene group or alkenylene group; B represents a single bond, -O-, -S- or -NH-; C represents an optionally substituted aryl or heteroaryl group; Q independently represents a carbon atom which a hydrogen atom or a substituent binds to, or a nitrogen atom.</p>
申请公布号 EP1813611(B1) 申请公布日期 2014.10.01
申请号 EP20050806938 申请日期 2005.11.17
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 YONEKUBO, SHIGERU;FUSHIMI, NOBUHIKO
分类号 C07D405/04;A61K31/404;A61K31/4166;A61K38/00;A61K38/28;A61K45/00;A61P1/10;A61P1/12;A61P3/04;A61P3/10;A61P7/10 主分类号 C07D405/04
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