发明名称 |
PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF |
摘要 |
The present invention relates to a process for preparing an N-substituted 1H-pyrazole-5-carboxylate compound of the formula (I-A) comprising the steps of i) deprotonating a compound of the formula (II) in which the variables R1, R2 and r are each as defined in the description and the claims, with a magnesium-organic base having a carbon bound magnesium; and ii) subjecting the product obtained in step (i) to a carbonylation by reacting it with a reagent selected from the group consisting carbon dioxide or a carbon dioxide equivalent, to obtain a compound of formula (I-A); and it relates to further conversions to yield a N-substituted 1H-pyrazole-5-carbonyl chloride compound of the formula (I) |
申请公布号 |
EP2782910(A1) |
申请公布日期 |
2014.10.01 |
申请号 |
EP20120794238 |
申请日期 |
2012.11.20 |
申请人 |
BASF SE |
发明人 |
DOCHNAHL, MAXIMILIAN;KÖRBER, KARSTEN;DESHMUKH, PRASHANT;KAISER, FLORIAN;RACK, MICHAEL;FRASSETTO, TIMO;VEITCH, GEMMA |
分类号 |
C07D401/04;C07D471/10 |
主分类号 |
C07D401/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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