| 发明名称 |
Targeted delivery of botulinum toxin to the sphenopalatine ganglion |
| 摘要 |
Botulinum toxin, among other presynaptic neurotoxins is used for the treatment and prevention of migraine and other headaches associated with vascular disorders. Presynaptic neurotoxins are delivered focally, targeting the sphenopalatine ganglion. Exemplary delivery is carried out by way of injection. |
| 申请公布号 |
US8846622(B2) |
申请公布日期 |
2014.09.30 |
| 申请号 |
US201313967500 |
申请日期 |
2013.08.15 |
| 申请人 |
Allergan, Inc. |
发明人 |
Blumenfeld Andrew M. |
| 分类号 |
A61K38/16;A61K38/00;A61K9/00;A61K38/48 |
主分类号 |
A61K38/16 |
| 代理机构 |
|
代理人 |
Phan Brigitte C.;Chan Ted;Condino Debra |
| 主权项 |
1. A method for reduction of pain associated with a headache in a mammal in need thereof, comprising the step of administering a therapeutically effective amount of a botulinum toxin to occipital nerve endings along the extracranial occipital artery, thereby effecting reduction of headache pain in the mammal in need thereof. |
| 地址 |
Irvine CA US |
