Sugar-coated preparation and production method for the same

摘要

A method is provided for producing a sugar-coated preparation including a solid composition containing a pharmacologically active ingredient and a sugar coating layer. The method comprises a step of forming the sugar coating layer with a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin. The sugar-coated preparation includes a solid composition containing a pharmacologically active ingredient and a sugar coating layer, wherein the sugar coating layer is made of a sugar coating composition containing one or more sugar-alcohols selected from the group consisting of mannitol and erythritol and a polyvinyl alcohol-based resin.

主权项

1. A sugar-coated preparation including a solid composition containing a pharmacologically active ingredient and a sugar coating layer,
wherein the sugar coating layer is made of a sugar coating composition consisting essentially of: one or more sugar-alcohols selected from the group consisting of mannitol and erythritol; and a polyvinyl alcohol-based resin selected from the group consisting of partially saponified polyvinyl alcohols having a degree of saponification of less than 97 mol %, completely saponified polyvinyl alcohols having a degree of saponification of 97 mol % or more, polyvinyl alcohol-polyethylene glycol graft copolymers and polyvinyl alcohol-acrylic acid-methyl methacrylate copolymers, wherein the mass ratio between the sugar-alcohol and the polyvinyl alcohol-based resin of the sugar coating composition is 15:4 to 15:20.