Method and apparatus for real-time 3D target position estimation by combining single x-ray imaging and external respiratory signals

摘要

A method and system are disclosed for estimating internal position information of a target in real-time based on a single gantry-mounted x-ray imager and a respiratory signal. The x-ray imaging is done periodically to limit radiation dosage. Initial parameters for the estimation model are determined in a pre-treatment session using four dimensional computed tomography (4D CT) in combination with a respiratory signal acquired from the patient. The model parameters are updated during treatment based on the periodic x-ray image data and the respiratory signal.

主权项

1. A method for real-time position estimation of an oncology target in a patient, comprising:
continuous monitoring of a respiratory signal of the patient; imaging of the target using an imaging device having a single source, the imaging being done periodically to limit radiation dosage administered by the single imaging device, each periodic image of the target being taken at a articular time from a corresponding particular direction with respect to the target; applying a model to estimate at the particular time for each said corresponding periodic image a centroid position of the target from a combination of said respiratory signal and target position data from said imaging; determining parameters of said model by using position displacement data from said imaging; and applying said model in real-time to a treatment program.