| 发明名称 | Method for treating synovial sarcoma | ||
| 摘要 | Methods of detecting synovial sarcoma using differentially expressed genes are disclosed. Also disclosed are methods of identifying agents for treating synovial sarcoma. Further, a method for treating or preventing a disease that is associated with Frizzled homologue 10 (FZD10) in a subject is provided. | ||
| 申请公布号 | US8846038(B2) | 申请公布日期 | 2014.09.30 |
| 申请号 | US201313918599 | 申请日期 | 2013.06.14 |
| 申请人 | Oncotherapy Science, Inc. | 发明人 | Nakamura Yusuke;Katagiri Toyomasa;Fukukawa Chikako;Kuhara Motoki |
| 分类号 | A61K39/395;C12Q1/68;C07K16/28 | 主分类号 | A61K39/395 |
| 代理机构 | Birch, Stewart, Kolasch & Birch, LLP | 代理人 | Birch, Stewart, Kolasch & Birch, LLP |
| 主权项 | 1. A method for treating synovial sarcoma that overexpresses Frizzled homologue 10 (FZD10) in a subject, comprising administering to the subject an effective amount of an antibody or antigen binding fragment thereof that specifically recognizes at least residues 43-56, 61-72, 156-169, 157-170, 157-172, 161-173, 174-191, 189-202, or 214-225, of the amino acid sequence shown in SEQ ID NO: 153. | ||
| 地址 | Kawasaki-shi JP | ||