Device, method and apparatus for performing separations

摘要

Embodiments of the present invention are directed to devices, methods and apparatus for performing separations in which particulates are separated or removed from a fluid stream flowing to a column. In one embodiment directed to a device, the invention includes a body (13) having a first surface (17) and a second surface (19) and at least one wall (23). At least one of the first surface (17) and second surface (19) is for receiving in sealing engagement a first conduit means. The remaining first surface (17) or second surface (19) is for engaging a column or a second conduit (19). The at least one wall (23) extends between the first surface (17) and the second surface (19). The body (13) has at least one opening (25) extending from the first surface (17) to the second surface (19) defining a chamber for receiving a solid phase separation media assembly (15). The device further includes a solid phase separation media assembly (15) within the chamber formed in the opening of the body between the first surface (17) and the second surface (19). The solid phase separation media assembly (15) is for removing particulates and undesired materials of a fluid flowing through the chamber. The body is constructed and arranged to fit in a body fitting to be attached to a column or which body fitting is part of an assembly for communicating with an column or a detector.

主权项

1. A device for performing one or more separations comprising:
a.) a cylindrical body having a cylindrical axis and a pair of end walls each perpendicular to said cylindrical axis, said cylindrical body having a side wall concentric with said cylindrical axis, said end walls and said side wall comprising surfaces of an integral body, wherein each of said end walls is deformable to receive in sealing engagement a conduit or a column, said cylindrical body having an opening extending between said end walls concentric with said cylindrical axis and a counterbore at each of said end walls that is concentric with said opening; and b.) a solid phase separation media assembly disposed in said opening and counterbores to remove particulates and undesired components of a fluid flowing through said cylindrical body, wherein an entirety of said side wall of said cylindrical body is configured to fit in a body fitting to be attached to an analytical column or is part of an assembly for communicating with a column, wherein the solid phase separation media assembly comprises a frit positioned in each of the counterbores below the surfaces of the end walls.