| 发明名称 | Amphiphilic macromolecules for nucleic acid delivery | ||
| 摘要 | The invention provides amphiphilic macromolecules that are useful for delivering nucleic acids to cells and that are useful as delivery agents for gene therapy. | ||
| 申请公布号 | US8846850(B2) | 申请公布日期 | 2014.09.30 |
| 申请号 | US201313801562 | 申请日期 | 2013.03.13 |
| 申请人 | Rutgers, the State University of New Jersey | 发明人 | Uhrich Kathryn E.;Sparks Sarah M.;Gu Li;Harmon Alex;Roth Charles M.;Federici Carolyn |
| 分类号 | C08G73/10;A61K48/00 | 主分类号 | C08G73/10 |
| 代理机构 | Viksnins Harris & Padys PLLP | 代理人 | Viksnins Harris & Padys PLLP |
| 主权项 | 1. A compound of formula I: wherein: B is the group —NH(-A-NH—)n—(CH2)2—NH—C(═O)-D-;each A is independently an ethylene group that is optionally substituted with one or more (C1-C3)alkyl groups;D is (C1-C6)alkylm is an integer from 0 to 100;n is an integer from 0 to 100;p is an integer from 1 to 200; andeach r is independently an integer from 0 to 20;or a salt thereof; and wherein the compound of formula I is not a compound of formula:or a salt thereof. | ||
| 地址 | New Brunswick NJ US | ||