| 摘要 |
FIELD: medicine.SUBSTANCE: invention refers to medicine and veterinary science, and can be used as an effective agent for the targeted delivery of DNA complexes with molecular conjugates into certain mammalian organs and tissues. The declared invention considerably improves the efficiency of the DNA delivery into the tumour cells and substantially simplifies, reduces the prices and time of molecular conjugate synthesis by using a module-based approach, as well as by providing a possibility of rapid alternation of ligand components for varying a conjugate affinity to various tumour and normal body cells.EFFECT: invention enables correcting the problem of tumour disease gene therapy, as the prepared module peptide conjugate is as shown by multiple real-time tests an effective agent for the targeted delivery, and most significantly, non-toxic, immunogenic and causes no side effects.2 cl, 7 dwg, 10 ex |
