| 发明名称 |
HUMAN GROWTH HORMONE RECEPTOR ANTAGONIST ANTIBODIES AND METHODS OF USE THEREOF. |
| 摘要 |
<p>The present invention provides antagonizing antibodies that bind to growth hormone receptor (GHR). The invention further relates to therapeutic methods for use of these antibodies to reduce IGF-1 levels and/or for the treatment and/or prevention of diseases associated with excessive IGF-1, including treatment of acromegaly, gigantism, cancer, diabetic nephropathy, arthritis, and lung inflammation.</p> |
| 申请公布号 |
MX2014007644(A) |
申请公布日期 |
2014.09.26 |
| 申请号 |
MX20140007644 |
申请日期 |
2012.12.10 |
| 申请人 |
RINAT NEUROSCIENCE CORPORATION |
发明人 |
CHAPARRO RIGGERS, JAVIER FERNANDO;SIEBEL, SARA IVA;PASCUA, EDWARD DERRICK;LIN, CHIA-YANG |
| 分类号 |
C07K16/28;A61K39/395;A61P35/00 |
主分类号 |
C07K16/28 |
| 代理机构 |
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