| 发明名称 |
6- (4- (1 -amino- 3 -hydroxycyclobutyl) phenyl) - 5 - phenyl (furo, thieno or pyrrolo) [2, 3-D] pyrimidin- 4 - one derivatives for the treatment of cancer |
| 摘要 |
<p>The present invention relates to compounds of Formula (I) that are useful as inhibitors of the activity of one or more isoforms of the serine / threonine kinase AKT. The present invention also relates to pharmaceutical compositions comprising these compounds and to methods of using these compounds in the treatment of cancer and methods of treating cancer.</p> |
| 申请公布号 |
AU2013237184(A1) |
申请公布日期 |
2014.09.25 |
| 申请号 |
AU20130237184 |
申请日期 |
2013.03.25 |
| 申请人 |
ALMAC DISCOVERY LIMITED |
发明人 |
HARRISON, TIMOTHY;O'DOWD, COLIN;SHEPHERD, STEVEN;TREVITT, GRAHAM;ZHANG, LIXIN;BURKAMP, FRANK |
| 分类号 |
C07D491/048;A61K31/519;A61P31/00;C07D487/04;C07D495/04 |
主分类号 |
C07D491/048 |
| 代理机构 |
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| 主权项 |
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