| 主权项 |
1. A method for the topical and/or local treatment of wounds caused by infections comprising administering a therapeutically effective amount of at least one compound of formula (I) in which
A is CH, CCl, CBr, C—CH3, C—CN, C—OCH3, C—OCHF2 or N,R1 is C1-5 alkyl, C1-5 alkenyl, 2-fluoroethyl, cycloalkyl, bicycloalkyl, 2-fluorocyclopropyl, 1-oxetan-3-yl, methylamino, optionally substituted phenyl or pyridyl, orA and R1 together form the group —C—O—CH2—CH(CH3)—,R2 is hydrogen or C1-3 alkyl optionally substituted by hydroxyl, halogen or amino,R3 is hydrogen, halogen, methyl, amino or NH—NH2,R4 is hydrogen, halogen or amino, andR5 is an optionally monosubstituted or polysubstituted mono-, bi- or tricyclic alicycle which is saturated or has at least one double bond and which optionally has at least one heteroatom in the ring system, or an aromatic mono-, bi- or tricycle optionally having at least one heteroatom, and/or at least one compound of formula (II) in which:
R1 is hydrogen or C1-3 alkyl, andR2 is an optionally monosubstituted or polysubstituted mono-, bi- or tricyclic alicycle which is saturated or has at least one double bond and which optionally has at least one heteroatom in the ring system, or an aromatic mono-, bi- or tricycle optionally having at least one heteroatom,and/or their corresponding hydrate and/or their corresponding physiologically compatible acid addition salt and/or optionally their corresponding physiologically compatible salt of the carboxylic acid of the compounds of formula (I) in which R2 is H and/or the compounds of formula (II) in which R1 is H, and/or corresponding enantiomers and/or corresponding diastereomers and/or corresponding racemates and/or a corresponding mixture of at least two of the above-mentioned compounds, and optionally other physiologically compatible auxiliary substances, to a subject in need thereof. |
