| 发明名称 |
HUMAN MONOCLONAL ANTIBODY WITH SPECIFICITY FOR DENGUE VIRUS SEROTYPE 1 E PROTEIN AND USES THEREOF. |
| 摘要 |
Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection. |
| 申请公布号 |
MX2013006710(A) |
申请公布日期 |
2014.09.25 |
| 申请号 |
MX20130006710 |
申请日期 |
2011.12.14 |
| 申请人 |
NATIONAL UNIVERSITY OF SINGAPORE |
发明人 |
PAUL ANTHONY MACARY;EE PING EVELYN TEOH;BRENDON JOHN HANSON;EN WEI TEO;ANGELINE PEI CHIEW LIM;MAH LEE MARY NG;SHEE MEI LOK;PETRA EVELIINA KUKKARO |
| 分类号 |
C07K16/10;A61K39/42;A61P31/14;C12N15/13;C12P21/08 |
主分类号 |
C07K16/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
