COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES TO ENTERIC PATHOGENS
摘要
Vaccine vectors capable of eliciting an immune response to enteric bacteria and methods of using the same are provided. The vaccine vectors include a polynucleotide encoding a PAL polypeptide. The PAL polypeptide may be expressed on the surface of the vaccine vector. The vaccine vector may also include a second polypeptide encoding an immunostimulatory polypeptide such as a CD 154 polypeptide or an HMGB1 polypeptide.
申请公布号
CA2906079(A1)
申请公布日期
2014.09.25
申请号
CA20142906079
申请日期
2014.03.14
申请人
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS;THE TEXAS A&M UNIVERSITY SYSTEM
发明人
BIELKE, LISA;LAYTON, SHERRYLL;HARGIS, BILLY;PUMFORD, NEIL R.;FAULKNER, OLIVIA B.;BERGHMAN, LUC;ABI-GHANEM, DAAD