| 主权项 |
1. A compound comprising a pyrrolidone residue covalently attached to two water-soluble, non-peptidic oligomers, the compound having the following structure.wherein;
each L is independently selected from the group consisting of hydrogen, hydroxyl, a C1-6 alkyl radical, a C2-6 alkenyl radical, and a C2-6 alkynyl radical; p is a whole number from 1 to 6; Y is selected from the group consisting of hydrogen, a C1-6 alkyl radical, a C2-6 alkenyl radical, and a C2-6 alkynyl radical; X1 is a first spacer moiety; X2 is a second spacer moiety; POLY1 is a first water-soluble, non-peptidic oligomer having a molecular weight of below about 1500 Daltons; and POLY2 is a second water-soluble, non-peptidic oligomer having a molecular weight of below about 1500 Daltons, and pharmaceutically acceptable salts thereof. |
