Detection of Auto-Antibodies to Specific Glycans as Diagnostic Tests for Autoimmune Diseases

摘要

The invention provides uses, methods, and kits for diagnosing an autoimmune disease, particularly scleroderma and systemic lupus erythematosus, in a subject by detecting the presence of one or more antibodies that specifically bind to one or more glycans in a subject sample.

主权项

1. A use of a glycan in the manufacture of an immunoassay for diagnosing an autoimmune disease in a subject comprising:
a glycan for contacting with a subject sample; and detecting binding of an antibody in the subject sample to the glycan, wherein binding of the antibody to the glycan is diagnostic for an autoimmune disease.