PASTEURELLA MULTOCIDA TOXIN RECOMBINANT PROTEIN AND USE THEREOF

摘要

The present invention relates to a Pasteurella multocida toxin recombinant protein and use thereof, the recombinant protein comprising at least one epitope of Pasteurella multocida toxin recombinant protein, and when the number of the epitopes is a plurality, the epitopes can be connected by a connector therebetween. The recombinant protein can further comprise the amino acid sequence of at least one unit of a complement cleavage C3d, and the epitopes and the amino acid sequence of the complement cleavage C3d can be connected by a connector. The present invention also relates to a nucleotide sequence encoding the above-mentioned Pasteurella multocida toxin recombinant protein, and a porcine atrophic rhinitis immunogenic composition comprising the above-mentioned Pasteurella multocida toxin recombinant protein.