| 发明名称 |
THYMIDINE KINASE DIAGNOSTIC ASSAY FOR GENE THERAPY APPLICATIONS |
| 摘要 |
Nucleic acid sequences encoding improved Herpes Simplex Virus Thymidine Kinases are provided, including their use in diagnostic and therapeutic applications. The thymidine kinases may be mutated using conservative mutations, non-conservative mutations, or both. Also provided are gene therapeutic systems, including viral and retroviral particles. |
| 申请公布号 |
CA2902975(A1) |
申请公布日期 |
2014.09.25 |
| 申请号 |
CA20142902975 |
申请日期 |
2014.03.14 |
| 申请人 |
EPEIUS BIOTECHNOLOGIES CORPORATION |
发明人 |
LEVY, JOHN P.;REED, REBECCA A.;MCNULTY, JOSEPH;JOHNSON, ROBERT G., JR. |
| 分类号 |
A01N63/00;A61K48/00;A61K49/00;C12N15/00 |
主分类号 |
A01N63/00 |
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