GLUCOSE AND INSULIN SENORS AND METHODS OF USE THEREOF

摘要

Described herein are glucose and insulin sensors. The sensors are composed of host cells with DNA specifically designed to produce fluorescence when the cells come into contact with glucose and/or insulin in the sample. Once the fluorescence has been quantified, it can be correlated with the amount of glucose and/or insulin present in the sample.

主权项

1. A sensor comprising a host cell comprising (1) a first DNA, wherein the first DNA comprises the following components in the following sequence: a glucose promoter, a glucose protein receptor, a ribosomal binding site, terminator, and a first reporter protein; (2) a second DNA, wherein the second DNA comprises the following components in the following sequence: an insulin promoter, a human insulin protein, a ribosomal binding site, a terminator, and a second reporter protein, or a combination thereof.