Asthma

摘要

The invention provides methods of providing a prognosis of asthma severity in children and young adults. More specifically, the invention relates to novel single nucleotide polymorphisms (SNPs), and the cumulative genetic association of these and other SNPs in various genes, with the prognosis of asthma severity. The invention also extends to kits and other prognostic tools used to provide the prognosis of asthma severity.

主权项

1. A method for providing a prognosis for an individual's asthma severity, the method comprising detecting, in a sample obtained from the individual, for the presence of a genetic polymorphism pattern in a matrix metalloproteinase 9 (MMP9) gene, wherein the polymorphism pattern is associated with asthma severity.