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1. A compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein m is 1; or 2; o is 1; 2; 3; or 4; Each R1 is independently selected from the group consisting of H; halogen; CN; C(O)OR2; OR2a; oxo (═O); C(O)R2; C(O)N(R2R2a); S(O)2N(R2R2a); S(O)N(R2R2a); S(O)2R2; S(O)R2; N(R2)S(O)2N(R2aR2b); N(R2)S(O)N(R2aR2b); SR2; N(R2R2a); NO2; OC(O)R2; N(R2)C(O)R2a; N(R2)S(O)2R2a; N(R2)S(O)R2a; N(R2)C(O)N(R2aR2b); N(R2)C(O)OR2a; OC(O)N(R2R2a); and C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more R3, which are the same or different; Optionally two R1 are joined to form together with the ring to which they are attached an 8 to 11 membered heterobicycle; R2, R2a, R2b are independently selected from the group consisting of H; C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different; R3 is halogen; CN; C(O)OR4; OR4; C(O)R4; C(O)N(R4R4a); S(O)2N(R4R4a); S(O)N(R4R4a); S(O)2R4; S(O)R4; N(R4)S(O)2N(R4aR4b); N(R4)S(O)N(R4aR4b); SR4; N(R4R4a); NO2; OC(O)R4; N(R4)C(O)R4a; N(R4)S(O)2R4a; N(R4)S(O)R4a N(R4)C(O)N(R4aR4b); N(R4)C(O)OR4a; or OC(O)N(R4R4a); R4, R4a, R4b are independently selected from the group consisting of H; and C1-6 alkyl, wherein C1-6alkyl is optionally substituted with one or more halogen, which are the same or different; T1 is phenyl; or 5 to 6 membered aromatic heterocycle, wherein T1 is substituted with N(R5a)C(O)N(R5bR5) or N(R5a)C(O)OR5 and optionally further substituted with one or more R6, which are the same or different; R6 is halogen; CN; C(O)OR7; OR7; C(O)R7; C(O)N(R7R7a); S(O)2N(R7R7a); S(O)N(R7R7a); S(O)2R7; S(O)R7; N(R7)S(O)2N(R7aR7b); N(R7)S(O)N(R7aR7b); SR7; N(R7R7a); NO2; OC(O)R7; N(R7)C(O)R7a; N(R7)S(O)2R7a; N(R7)S(O)R7a; N(R7)C(O)N(R7aR7b); N(R7)C(O)OR7a; OC(O)N(R7R7a); or C1-6 alkyl, wherein C1-6alkyl is optionally substituted with one or more halogen, which are the same or different; R5a, R5b, R7, R7a, R7b are independently selected from the group consisting of H; C1-6alkyl, wherein C1-6alkyl is optionally substituted with one or more halogen, which are the same or different; R5 is H; T2; and C1-6alkyl, wherein C1-6alkyl is optionally substituted with one or more R8, which are the same or different; R8 is halogen; CN; C(O)OR9; OR9; C(O)R9; C(O)N(R9R9a); S(O)2N(R9R9a); S(O)N(R9R9a); S(O)2R9; S(O)R9; N(R9)S(O)2N(R9aR9b); N(R9)S(O)N(R9aR9b); SR9; N(R9R9a); NO2; OC(O)R9; N(R9)C(O)R9a; N(R9)S(O)2R9a; N(R9)S(O)R9a N(R9)C(O)N(R9aR9b); N(R9)C(O)OR9a; OC(O)N(R9R9a); or T2; R9, R9a, R9b are independently selected from the group consisting of H; and C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different; Optionally R5, R5b are joined to form together with the nitrogen atom to which they are attached an at least the nitrogen atom as ring heteroatom containing 4 to 7 membered heterocyclyl ring; or 8 to 11 membered heterobicyclyl ring, wherein the 4 to 7 membered heterocyclyl ring; and the 8 to 11 membered heterobicyclyl ring are optionally substituted with one or more R10, which are the same or different; T2 is C3-7cycloalkyl; 4 to 7 membered heterocyclyl; 8 to 11 membered heterobicyclyl; phenyl; naphthyl; indenyl; or indanyl, wherein T2 is optionally substituted with one or more R10, which are the same or different; R10 is halogen; CN; C(O)OR11; OR; oxo (═O), where the ring is at least partially saturated; C(O)R11; C(O)N(R11R11a); S(O)2N(R11R11a); S(O)N(R11R11a); S(O)2R11; S(O)R11; N(R11)S(O)2N(R11aR11b); N(R11)S(O)N(R11aR11b); SR11; N(R11R11a); NO2; OC(O)R11; N(R11)C(O)R11a; N(R11)S(O)2R11a; N(R11)S(O)R11a; N(R11)C(O)N(R11aR11b); N(R11)C(O)OR11a; OC(O)N(R11R11a); or C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more R12, which are the same or different; R11, R11a, R11b are independently selected from the group consisting of H; C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different; R12 is halogen; CN; C(O)OR13; OR13; C(O)R13; C(O)N(R13R13a); S(O)2N(R13R13a); S(O)N(R13R13a); S(O)2R3; S(O)R13; N(R13)S(O)2N(R13aR13b); N(R13)S(O)N(R13aR13b); SR13; N(R13R13a); NO2; OC(O)R13; N(R13)C(O)R13a; N(R13)S(O)2R13a; N(R13)S(O)R13a; N(R13)C(O)N(R13aR13b); N(R13)C(O)OR13a; or OC(O)N(R13R13a); R13, R13a, R13b are independently selected from the group consisting of H; and C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different; Ra, Rb are joined to form —(CR14R14a)p—S(O)r(CR14bR14c)q—; r is 0; 1; or 2; p, q are 0; 1; 2; or 3, provided that p+q is 2; 3; or 4; R14, R14a, R14b, R14c are independently selected from the group consisting of H; halogen; CN; C(O)OR15; OR15; C(O)R15; C(O)N(R15R15a); S(O)2N(R15R15a); S(O)N(R15R15a); S(O)2R15; S(O)R15; N(R15)S(O)2N(R15aR15b); N(R15)S(O)N(R15aR15b); SR15; N(R15R15a); NO2; OC(O)R15; N(R15)C(O)R15a; N(R15)S(O)2R15a; N(R15)S(O)R15a; N(R15)C(O)N(R15aR15b); N(R15)C(O)OR15a; OC(O)N(R15R5a); or C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more R16, which are the same or different; Optionally one of the pairs R14, R14a and R14b, R14c or both pairs form an oxo group (═O); Optionally one of the pairs selected from the group consisting of R14, R14a; R14, R14b; two adjacent R14, in case p>1; and two adjacent R14b, in case q>1, are joined to form together with the ring to which they are attached an 6 to 11 membered heterobicycle; R15, R15a, R15b are independently selected from the group consisting of H; C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different; R16 is halogen; CN; C(O)OR17; OR17; C(O)R17; C(O)N(R17R17a); S(O)2N(R17R17a); S(O)N(R17R17a); S(O)2R17; S(O)R17; N(R17)S(O)2N(R17aR17b); N(R17)S(O)N(R17aR17b); SR17; N(R17R17a); NO2; OC(O)R17; N(R17)C(O)R17a; N(R17)S(O)2R17a; N(R17)S(O)R17a; N(R17)C(O)N(R17aR17b); N(R17)C(O)OR17a; or OC(O)N(R17R17a); R17, R17a, R17b are independently selected from the group consisting of H; C1-6 alkyl, wherein C1-6 alkyl is optionally substituted with one or more halogen, which are the same or different. |
