LUMINESCENT TRIAZACYCLONONANE-BASED LANTHANIDE CHELATE COMPLEXES AS LABELLING REAGENTS

摘要

The invention relates to a detectable molecule comprising a biospecific binding reactant attached to a macrocyclic luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of the formula (I) wherein, R1 consists of a linker coupling the chelate to the biospecific binding reactant and optionally a spacer; either R3 or R4 is H; and the lanthanide ion Ln3+ is europium(lll) or samarium(lll). The invention also relates to corresponding lanthanide chelates. The invention further relates to the use of the detectable molecule of the invention.