This invention relates to methods of subcutaneous administration of ADAMTS13 formulations to a treat a disease or condition associated with ADAMTS13 and VWF dysfunction. Furthermore, evidence of the unexpectedly high bioavailability of ADAMTS13 formulations administered subcutaneously is provided herein.
申请公布号
CA2905058(A1)
申请公布日期
2014.09.25
申请号
CA20142905058
申请日期
2014.03.13
申请人
BAXALTA INCORPORATED;BAXALTA GMBH
发明人
SCHIVIZ, ALEXANDRA NATHALIE;HOELLRIEGL, WERNER;PLAIMAUER, BARBARA;ROTTENSTEINER, HANSPETER;MUCHITSCH, EVA-MARIA