ACF DETECTION METHOD

摘要

The present invention provides a method for detecting ACF by analyzing a test region of large intestine tissue at the molecular level. Namely, the present invention relates to a method for detecting aberrant crypt foci (ACF) that comprises detecting an ACF detection marker in a test region of large intestine tissue, by using one or more types of molecules for which ACF-specific expression increases as the ACF detection marker, the molecule being selected from the group consisting of SLC2a1, and SLC7a7; an ACF detection marker for detecting the ACF in human-derived large intestine tissue, that is SLC2a1, or SLC7a7; and, a method for evaluating risk of colorectal cancer and colorectal adenoma in subjects based on the results of detecting ACF in a test region of large intestine tissue of the subjects using the aforementioned ACF detection method.

主权项

1. A method for detecting aberrant crypt foci (ACF), comprising:
detecting one or more types of molecules for which ACF-specific expression increases, and selected from the group consisting of SLC2a1 and SLC7a7 as an ACF detection marker, in a test region of large intestine tissue of an animal.