| 发明名称 |
NOROVIRUS VACCINE FORMULATIONS |
| 摘要 |
The present invention relates to antigenic and vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to a process for the production of both monovalent and multivalent VLPs, the VLPs comprising capsid proteins from one or more Norovirus genogroups. |
| 申请公布号 |
US2014286994(A1) |
申请公布日期 |
2014.09.25 |
| 申请号 |
US201313836446 |
申请日期 |
2013.03.15 |
| 申请人 |
LIGOCYTE PHARMACEUTICALS, INC. |
发明人 |
RICHARDSON Charles;VEDVICK Thomas S.;FOUBERT Thomas R. |
| 分类号 |
A61K39/12 |
主分类号 |
A61K39/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of generating an immune response to at least two Norovirus strains by administering to a patient an antigenic formulation comprising a combination of two or more monovalent Norovirus VLPs of different Norovirus genotypes, or an antigenic formulation comprising multivalent VLPs containing capsid proteins from two or more different Norovirus genotypes, such that the combination of VLPs within the formulation does not block the immunogenicity of each VLP type. |
| 地址 |
Boxeman MT US |
