发明名称 MACROCYCLIC PROLINE DERIVED HCV SERINE PROTEASE INHIBITORS
摘要 The present invention discloses compounds of Formula I or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
申请公布号 ZA201302317(B) 申请公布日期 2014.09.25
申请号 ZA20130002317 申请日期 2013.03.27
申请人 ENANTA PHARMACEUTICALS, INC 发明人 OR YAT SUN;WANG GUOQIANG;WANG BIN;MA JUN;LONG JIANG
分类号 A61K 主分类号 A61K
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