发明名称 PROCESS FOR PREPARING METHYL METHYLCARBAMATE AND ITS PURIFICATION FOR USE AS PHARMACEUTICALLY ACTIVE COMPOUND
摘要 The present invention relates to a process for preparing methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate of the formula (I);;and to a process for purifying the crude product of the compound of the formula (I) for use as pharmaceutically active compound, where, for purification, methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}methylcarbamate sulphinyldimethane (1:1), i.e. a compound of the formula (II), is isolated as intermediate or is generated as intermediate in this purification process, if appropriate present in a mixture.
申请公布号 US2014288303(A1) 申请公布日期 2014.09.25
申请号 US201414295922 申请日期 2014.06.04
申请人 Bayer Intellectual Property GmbH 发明人 MAIS Franz-Josef;Rehse Joachim;Joentgen Winfried;Siegel Konrad
分类号 C07D471/04 主分类号 C07D471/04
代理机构 代理人
主权项
地址 Monheim DE