发明名称 |
N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE |
摘要 |
The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is absent or present, and when present is -C(O)- or -C(O)NH-; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is -C(O)-, or a pharmaceutically acceptable salt thereof. |
申请公布号 |
WO2014151959(A1) |
申请公布日期 |
2014.09.25 |
申请号 |
WO2014US26730 |
申请日期 |
2014.03.13 |
申请人 |
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;PETRUKHIN, KONSTANTIN;CIOFFI, CHRISTOPHER;JOHNSON, GRAHAM;DOBRI, NICOLETA;FREEMAN, EMILY;CHEN, PING;CONLON, MICHAEL;ZHU, LEI |
发明人 |
PETRUKHIN, KONSTANTIN;CIOFFI, CHRISTOPHER;JOHNSON, GRAHAM;DOBRI, NICOLETA;FREEMAN, EMILY;CHEN, PING;CONLON, MICHAEL;ZHU, LEI |
分类号 |
A61K31/454;C07D401/02 |
主分类号 |
A61K31/454 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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