发明名称 N-ALKYL-2-PHENOXYETHANAMINES, THEIR PREPARATION AND USE
摘要 The present invention provides a compound having the structure: (structurally represented) wherein R1, R2, R3, R4, and R5 are each independently H, halogen, CF3 or C1-C4 alkyl; R6 is alkyl; A is absent or present, and when present is -C(O)- or -C(O)NH-; B is substituted or unsubstituted monocycle, bicycle, heteromonocycle, heterobicycle, benzyl, CO2H or (C1-C4 alkyl)-CO2H, wherein when B is CO2H, then A is present and is -C(O)-, or a pharmaceutically acceptable salt thereof.
申请公布号 WO2014151959(A1) 申请公布日期 2014.09.25
申请号 WO2014US26730 申请日期 2014.03.13
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK;PETRUKHIN, KONSTANTIN;CIOFFI, CHRISTOPHER;JOHNSON, GRAHAM;DOBRI, NICOLETA;FREEMAN, EMILY;CHEN, PING;CONLON, MICHAEL;ZHU, LEI 发明人 PETRUKHIN, KONSTANTIN;CIOFFI, CHRISTOPHER;JOHNSON, GRAHAM;DOBRI, NICOLETA;FREEMAN, EMILY;CHEN, PING;CONLON, MICHAEL;ZHU, LEI
分类号 A61K31/454;C07D401/02 主分类号 A61K31/454
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