| 摘要 |
A zero flow responsive heart stimulator contains a zero flow sensors, which generate signals at the moment of the termination of blood inflow in the right atrium and the right ventricle, sensing this the most precisely in the places, where the sinoatrial node and atrioventricular node reside, for the right atrium and the right ventricle, respectively. The stimulator is based on our discovery, that the two nodes are the same sensors in the biological systems, based on the fact that until the filling of the said two chambers continues, the venous blood flow sucks on Bernoulli's principle the Ca and Na cations from the two nodes interstices, preventing the inward currant in their cells, thus delaying the completion of the 0-phase of their depolarization and the action potential, until the blood flow stops. Our discovery proves that the alternating flow/no flow of the blood in the orifice of superior vena cava and the entrance of the right ventricle is the real pacemaker that fires the both nodes, but not the inverse, as generally assumed, approximating the natural pacemaker to a clock mechanism. This, together with the discovered by us arteriovenous, arteriolymphatic and capillary pumps, closes the loop of the autonomous automatic functioning of the cardiovascular system, even completely denervated and in the absence of muscle contractions. It is the first devise, which activates the atrial and the ventricular contractions in a function of the zero-flow of the filling them venous blood, which is the exact imitation of the sinoatrial and atrioventricular firing. |
| 主权项 |
1. A zero flow responsive cardiac pacemaker comprising:
an electrode means for in vivo delivery of stimulation pulses to a heart; a pulse generator means, connected to said electrode means, for emitting said stimulation pulses simultaneous with the signals supplied by the zero flow sensing means, said pulse generator means having control input; a zero flow sensing means for generating signals identifying the zero flow of blood at a given place in the heart chambers or in superior vena cava, supplying these signals to the said control input, for generating pulses simultaneous with these zero flow signals. |
