Method For Using Exhaled Breath to Determine the Presence of Drug

摘要

The present invention provides a method for determining the presence and/or the level of drug in a subject's system using exhaled breath of the subject.

主权项

1. A method for determining the level of drug in a subject's system, said method comprising:
(i) collecting more than 95% of all aerosol particles from exhaled breath of a subject by having the subject exhale into a breath sample collecting apparatus and measuring the total volume of exhaled breath exhaled into the breath sample collecting apparatus; (ii) determining the amount of a drug metabolite present in the collected aerosol particles; (iii) normalizing the amount of the drug metabolite in the collected aerosol particles based on the volume of exhaled breath; and (iv) determining the level of drug in the subject's system by using the normalized amount of the drug metabolite determined in said step (iii).