The invention relates to a pharmaceutical formulation comprising 40-O-(2-hydroxy)ethyl-rapamycin in a high drug load part and an immediate release part. In addition, the invention relates to a formulation comprising 40-O-(2-hydroxy)ethyl-rapamycin in a first layer and a surfactant in a layer beneath the first layer. The pharmaceutical composition is particularly suitable for use as a medicament.
申请公布号
WO2014147567(A1)
申请公布日期
2014.09.25
申请号
WO2014IB59965
申请日期
2014.03.19
申请人
NOVARTIS AG;DIEDERICH, ANKE;KUNZLER, HANS-ULRICH;GRANER, OLIVER
发明人
DIEDERICH, ANKE;KUNZLER, HANS-ULRICH;GRANER, OLIVER