发明名称 |
ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF |
摘要 |
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody: |
申请公布号 |
EP2461830(B1) |
申请公布日期 |
2014.09.24 |
申请号 |
EP20100739817 |
申请日期 |
2010.08.02 |
申请人 |
MEDAREX, L.L.C. |
发明人 |
CHENG, HENG;CONG, QIANG;GANGWAR, SANJEEV;ZHANG, QIAN |
分类号 |
A61K47/48;C07K5/02;C07K5/06 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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