发明名称 |
MARKERS OF TRIPLE-NEGATIVE BREAST CANCER AND USES THEREOF |
摘要 |
<p>In one aspect provided herein are methods of determining a triple negative breast cancer (TNBC) subtype in an individual in need thereof comprising determining expression of one or more genes in one or more TNBC cells of the individual; and comparing the expression of the one or more genes in the TNBC cells with the expression of the one or more genes in a control. In another aspect, the methods are directed to methods of determining a treatment protocol for the TNBC patient based on the TNBC subtype. In another aspect, the methods are directed to predicting whether an individual will benefit from a treatment for a particular TNBC subtype. In yet another aspect, the invention is directed to a method of determining whether an agent can be used to treat a TNBC subtype.</p> |
申请公布号 |
EP2780469(A1) |
申请公布日期 |
2014.09.24 |
申请号 |
EP20120798526 |
申请日期 |
2012.11.17 |
申请人 |
VANDERBILT UNIVERSITY |
发明人 |
PIETENPOL, JENNIFER, A.;LEHMANN, BRIAN;BAUER, JOSH;CHEN, XI |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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