发明名称 |
CRYSTAL FORM OF (6S)-5-METHYLTETRAHYDROFOLATE SALT AND METHOD FOR PREPARING SAME |
摘要 |
Disclosed are a crystal form of (6S)-5-methyltetrahydrofolate salt and a method for preparing the same. The crystal form is: Form C of the crystal form of (6S)-5-methyltetrahydrofolate calcium salt, where the X-ray diffraction pattern has diffraction peaks at the 2¸ angles of 6.3±0.2 and 19.2±0.2; or the crystal form of (6S)-5-methyltetrahydrofolate strontium salt, where the X-ray diffraction pattern has diffraction peaks at the 2¸ angles of 6.5±0.2 and 22.0±0.2. The crystal form of (6S)-5-methyltetrahydrofolate salt of the present invention has the advantages of excellent physicochemical properties, good stability, high purity, good reproducibility, and being more suitable for production on an industrial scale. |
申请公布号 |
KR20140113740(A) |
申请公布日期 |
2014.09.24 |
申请号 |
KR20147023261 |
申请日期 |
2012.12.17 |
申请人 |
LIANYUNGANG JINKANG HEXIN PHARMACEUTICAL CO., LTD. |
发明人 |
WANG ZHEQING;CHENG YONGZHI;HUANG HENG;LI HUIZHEN |
分类号 |
C07D475/04;A61K31/519;A61P7/06;A61P9/00 |
主分类号 |
C07D475/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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