发明名称 INDOLE/BENZIMIDAZOLE COMPOUNDS AS MTOR KINASE INHIBITORS
摘要 The present invention provides compounds of formula (I) (see formula I) that are kinase inhibitors, specifically PIK kinase inhibitors, more specifically, mTOR inhibitors and are therefore useful for the treatment of diseases treatable by inhibition of kinases, specifically PIK kinase inhibitors, more specifically, mTOR such as cancer. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.
申请公布号 CA2752527(C) 申请公布日期 2014.09.23
申请号 CA20102752527 申请日期 2010.02.10
申请人 AMGEN INC. 发明人 BOEZIO, ALESSANDRO;CHENG, ALAN C.;COATS, JAMES R.;COPELAND, KATRINA W.;GRACEFFA, RUSSELL;HARMANGE, JEAN-CHRISTOPHE;HUANG, HONGBING;LA, DANIEL;OLIVIERI, PHILIP R.;PETERSON, EMILY A.;SCHENKEL, LAURIE
分类号 C07D403/04;A61K31/53;A61P35/00;C07D403/14 主分类号 C07D403/04
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