| 发明名称 | Method for preparing trans-{4-[(alkylamino) methyl]- cyclohexyl}acetic acid ester | ||
| 摘要 | A method for preparing a trans-{4-[(alkylamino)methyl]cyclohexyl}acetic acid, which is useful as a raw material compound for manufacture of medicaments and the like, comprising the step of reducing amide group of a compound represented by the following general formula (6) (R1 represents hydrogen atom or a C1-6 alkyl group, and R2 represents a C1-6 alkyl group, a C3-6 cycloalkyl group, a (C3-6 cycloalkyl)(C1-6 alkyl) group, a C6-10 aryl group, or a C7-12 aralkyl group).; | ||
| 申请公布号 | US8841478(B2) | 申请公布日期 | 2014.09.23 |
| 申请号 | US200913131767 | 申请日期 | 2009.11.27 |
| 申请人 | Kowa Company, Ltd. | 发明人 | Kusakabe Taichi;Yamazaki Koichi;Ohgiya Tadaaki;Shibuya Kimiyuki |
| 分类号 | C07C233/48;C07C227/16;C07C231/12;C07C231/02 | 主分类号 | C07C233/48 |
| 代理机构 | Greenblum & Bernstein, P.L.C. | 代理人 | Greenblum & Bernstein, P.L.C. |
| 主权项 | 1. A method for preparing a trans-{4-[(alkylamino)methyl]cyclohexyl}acetic acid ester represented by the following general formula (1): wherein R1 represents a hydrogen atom or a C1-6 alkyl group, and R2 represents a C1-6 alkyl group, a C3-6 cycloalkyl group, a (C3-6 cycloalkyl)(C1-6 alkyl) group, a C6-10 aryl group, or a C7-12 aralkyl group, which comprises reducing the amide group of a compound represented by the following general formula (6): (R1 and R2 in the formula have the same meanings as those defined above). | ||
| 地址 | Aichi JP | ||