发明名称 |
Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
摘要 |
This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy. |
申请公布号 |
US8841330(B2) |
申请公布日期 |
2014.09.23 |
申请号 |
US201213368812 |
申请日期 |
2012.02.08 |
申请人 |
Bayer Healthcare LLC |
发明人 |
Riedl Bernd;Dumas Jacques;Khire Uday;Lowinger Timothy B.;Scott William J.;Smith Roger A.;Wood Jill E. |
分类号 |
A61K31/44 |
主分类号 |
A61K31/44 |
代理机构 |
Millen, White, Zelano & Branigan, P.C. |
代理人 |
Millen, White, Zelano & Branigan, P.C. |
主权项 |
1. A method for the treatment of a tumor of the prostate, breast, liver, ovary or cervix in a human or animal comprising administering an effective amount of
N-(4-chloro-3-(trifluoromethyl)phenyl)-N′-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea of the formula:or a pharmaceutically acceptable salt thereof. |
地址 |
Whippany NJ US |