发明名称 Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
摘要 This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
申请公布号 US8841330(B2) 申请公布日期 2014.09.23
申请号 US201213368812 申请日期 2012.02.08
申请人 Bayer Healthcare LLC 发明人 Riedl Bernd;Dumas Jacques;Khire Uday;Lowinger Timothy B.;Scott William J.;Smith Roger A.;Wood Jill E.
分类号 A61K31/44 主分类号 A61K31/44
代理机构 Millen, White, Zelano & Branigan, P.C. 代理人 Millen, White, Zelano & Branigan, P.C.
主权项 1. A method for the treatment of a tumor of the prostate, breast, liver, ovary or cervix in a human or animal comprising administering an effective amount of N-(4-chloro-3-(trifluoromethyl)phenyl)-N′-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea of the formula:or a pharmaceutically acceptable salt thereof.
地址 Whippany NJ US