主权项 |
1. A substituted pyran compound having the structural formula I:or a pharmaceutically acceptable salt, ester, carbamate, imide, or amide thereof, wherein
A and A′ are individually selected from the group consisting of optionally substituted C4-C14 aryl and heteroaryl wherein heteroatoms of heteroaryl A and/or A′ are selected from the group consisting of O, N, and S; Z is a chemical bond or —Y—(CH2)o—; Y is NH or O; o is 0, 1, 2, 3, or 4; R is H, C1-8 alkyl, C2-8 alkenyl, or C2-8 alkynyl; W is —OH or —NHR; B is optionally substituted C4-C14 aryl or optionally substituted C4-C14 heteroaryl; and n and m are each independently 0, 1, 2, 3, or 4. |