Patch production technology

摘要

The invention relates to a transdermal patch with a release liner film, an active substance layer with the active substance rotigotine, and/or one of its pharmacologically acceptable salts, and a carrier layer, wherein the active substance layer is placed between the release liner film and the carrier layer. The invention further relates to a process for manufacturing of a transdermal patch, as well as a tool for producing a patch of this type.

主权项

1. A transdermal patch, comprising
a release liner film, a polymer layer containing a non-crystalline active substance, and a carrier layer, wherein the active substance layer is between the release liner film and the carrier layer, the release liner film and/or the carrier layer comprising at least one peripheral separating edge with none of the polymer layer therebetween, wherein the release liner film and the carrier layer are thermally and detachably directly connected to each other over a length of at least 70% of the peripheral separating edge, such that the polymer layer is sealed by said thermally and detachably connected peripheral separating edge.