发明名称 |
Human antibodies specifically binding to the hepatitis B virus surface antigen |
摘要 |
Provided are antibodies specifically binding to the HBV surface antigen (HBsAg) which are effective for the prevention or treatment of hepatitis B. |
申请公布号 |
US8840895(B2) |
申请公布日期 |
2014.09.23 |
申请号 |
US201013518683 |
申请日期 |
2010.07.08 |
申请人 |
Green Cross Corporation |
发明人 |
Kim Se-Ho;Chang Ki Hwan;Hong Kwang-Won;Shin Yong-Won;Kim Min-soo;Lee Hae-Won;Ryoo Kyung Hwan;Seo Dong Hyuck;Kim Jean Man;Shin Yong Nam;Koo Sunmi;Lim Jung-Ae;Lee Mijung;Lee Yeon Kyung;Seo Misun |
分类号 |
A61K39/42;C12N5/07;C07H21/04;C07K16/08;A61K39/00 |
主分类号 |
A61K39/42 |
代理机构 |
Sughrue Mion, PLLC |
代理人 |
Sughrue Mion, PLLC |
主权项 |
1. A human antibody specifically binding to hepatitis B virus surface antigen, comprising:
a) a heavy chain variable region having the amino acid sequence of SEQ ID NO: 1; b) a light chain variable region having any of the amino acid sequences of SEQ ID NOs: 2, 3, and 4; c) a heavy chain constant region; and d) a light chain constant region. |
地址 |
Gyeonggi-Do KR |